Generic
Name
Trade
Name
Drug
Class
Abbrev. Drug
Company
FDA-
Approved
Usual
Dosage
Common Side Effects
zidovudine Retrovir nucleoside reverse
transcriptase inhibitor
AZT, ZDV Glaxo Yes 200mg TID bone marrow suppression, GI upset, headache, myopathy
zidovudine-
lamivudine
Combivir two nucleoside RTIs AZT/3TC Glaxo Yes 1 pill BID same as above
didanosine Videx nucleoside RTI ddI Bristol Yes 200 mg BID peripheral neuropathy, pancreatitis, diarrhea (take on empty stomach)
zalcitabine HIVID nucleoside RTI ddC Roche Yes 0.75mg TID peripheral neuropathy, pancreatitis, oral ulcers
stavudine Zerit nucleoside RTI d4T Bristol Yes 40mg BID peripheral neuropathy
lamivudine Epivir nucleoside RTI 3TC® Glaxo Yes 150mg BID anemia, GI upset
saquinavir Invirase nucleoside RTI SQV Roche Yes 600mg TID (take with a fatty snack)
indinavir Crixivan protease inhibitor IDV Merck Yes 800mg TID kidney stones (take on empty stomach)
ritonavir Norvir protease inhibitor RTV Abbott Yes 600mg BID GI upset (refrigerate medication)
nelfinavir VIRACEPT protease inhibitor NLF Agouron Yes 750mg TID diarrhea
nevirapine Viramune non-nucleoside RTI NVP BIPI Yes 200mg BID rash
delavirdine Rescriptor non-nucleoside RTI DLV Pharmacia Yes 400mg TID rash
Efavirenz Sustiva non-nucleoside RTI EFV DuPont-
Merck
Yes TBD dizziness, vivid dreams, transient rash
amprenavir Agenerase protease inhibitor APV Yes 1200 BID rash, GI upset, diarrhea
abacavir Ziagen nucleoside RTI ABC Glaxo Yes 300 BID hypersensitivity reaction (do not rechallenge)
hydroxyurea Hydrea ribonucleotide
reductase inhibitor
HU Not for
HIV
500 BID bone marrow suppression, peripheral neuropathy, aphthous ulcers
adefovir Preveon nucleotide analogue ADV Gilead No 120mg QD GI upset